Natural killer cells in host defense against veterinary pathogens
نویسندگان
چکیده
منابع مشابه
Natural Killer cells in Innate Defense against Infective Pathogens
Infectious diseases cause over 300 million illnesses and more than 5 million deaths each year worldwide. Understanding how components of the host immune system function to control disease-causing pathogens is critically important to develop strategies for preventing and controlling these diseases. With the discovery of innate immune receptors, we are beginning to appreciate the important role o...
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BACKGROUND In recent years, the fungal infectious disease zygomycosis has increased in incidence worldwide, especially among the immunodeficient population. Despite the rates of zygomycosis-related death and deformation being very high, the mechanism(s) by which the fungal pathogens cause these severe manifestations remain unknown. METHODS Using the associated Rhizomucor variabilis species, w...
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Natural killer (NK) cells have innate antibacterial activity that could be targeted for clinical interventions for infectious disease caused by naturally occurring or weaponized bacterial pathogens. To determine a potential role for NK cells in immunity to Bacillus anthracis, we utilized primary human and murine NK cells, in vitro assays, and in vivo NK cell depletion in a murine model of inhal...
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Background: Schizophrenia has been associated with altered immunity. Different studies regarding natural killer cell activity (NKA) in schizophrenic patients have shown inconsistent results. Objectives: To evaluate NK cell activity in schizophrenic patients in comparison with healthy control individuals. Methods: 30 medication-free schizophrenic patients and 41 healthy sex, age and smoking st...
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Uropathogenic Escherichia coli (UPEC) are a common cause of urinary tract infections (UTIs) in humans. While the importance of natural killer (NK) cells in innate immune protection against tumors and viral infections is well documented, their role in defense against bacterial infections is still emerging, and their involvement in UPEC-mediated UTI is practically unknown. Using a systematic muta...
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ژورنال
عنوان ژورنال: Veterinary Immunology and Immunopathology
سال: 2015
ISSN: 0165-2427
DOI: 10.1016/j.vetimm.2015.10.001